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1

Discovery of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa1

Pinto, Donald J. P., Orwat, Michael J., Wang, Shuaige, Fevig, John M., Quan, Mimi L., Amparo, Eugene, Cacciola, Joseph, Rossi, Karen A., Alexander, Richard S., Smallwood, Angela M.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 320 KB

english, 2001

2

1-[3-Aminobenzisoxazol-5′-yl]-3-trifluoromethyl-6-[2′-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1′]-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa

Donald J.P. Pinto, Michael J. Orwat, Mimi L. Quan, Qi Han, Robert A. Galemmo Jr., Eugene Amparo, Brian Wells, Christopher Ellis, Ming Y. He, Richard S. Alexander, Karen A. Rossi, Angela Smallwood, Pan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 184 KB

english, 2006

3

Phenyltriazolinones as potent factor Xa inhibitors

Mimi L. Quan, Donald J.P. Pinto, Karen A. Rossi, Steven Sheriff, Richard S. Alexander, Eugene Amparo, Kevin Kish, Robert M. Knabb, Joseph M. Luettgen, Paul Morin, Angela Smallwood, Francis J. Woerner,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

4

The discovery and structure–activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase

Matthew G. LaPorte, Tandy L. Draper, Lori E. Miller, Charles W. Blackledge, Lara K. Leister, Eugene Amparo, Alison R. Hussey, Dorothy C. Young, Srinivas K. Chunduru, Christopher A. Benetatos, Gerry Rh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

5

Design and synthesis of potent and selective 5,6-fused heterocyclic thrombin inhibitors

Celia Dominguez, Daniel E. Duffy, Qi Han, Richard S. Alexander, Robert A. Galemmo Jr., Jeongsook M. Park, Pancras C. Wong, Eugene C. Amparo, Robert M. Knabb, Joseph Luettgen, Ruth R. Wexler

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 338 KB

english, 1999

6

Gynecologic masses: Value of magnetic resonance imaging

Hricak, Hedvig, Lacey, Conley, Schriock, Eldon, Fisher, Madeleine R., Amparo, Eugene, Dooms, George, Jaffe, Robert

Journal:

American Journal of Obstetrics and Gynecology

Year:

1985

Language:

english

File:

PDF, 2.11 MB

english, 1985

7

A Noncleavable Retro-Binding Peptide That Spans the Substrate Binding Cleft of Serine Proteases. Atomic Structure of Nazumamide A: Human Thrombin ‡

Nienaber, Vicki L., Amparo, Eugene C.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 151 KB

english, 1996

8

Magnetic resonance imaging in clinical practice

Margulis, Alexander R., Amparo, Eugene

Journal:

Postgraduate Medicine

Year:

1985

Language:

english

File:

PDF, 705 KB

english, 1985

9

MR Imaging of Transverse/Sigmoid Dural Sinus and Jugular Vein Thrombosis

McArdle, Craig B., Mirfakhraee, Mansour, Amparo, Eugenic G., Kulkarni, Madan V.

Journal:

Journal of Computer Assisted Tomography

Year:

1987

File:

PDF, 573 KB

1987

10

Benign Urachal Cyst in an Adult

Amparo, Eugenic G., Cohen, Marc S., Fagan, Charles J.

Journal:

Journal of Computer Assisted Tomography

Year:

1982

File:

PDF, 191 KB

1982